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KMID : 1094720210260040529
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Biotechnology and Bioprocess Engineering
2021 Volume.26 No. 4 p.529 ~ p.545
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Nanostructure Materials: Efficient Strategies for Circulating Tumor Cells Capture, Release, and Detection
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Asghari Sahar
Barati Fatemeh
Avatefi Manizheh
Mahmoudifard Matin
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Abstract
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It has been proved that most of the deaths due to cancer are related to metastasis. This process occurs through the separation of cells from the primary tumor and maintenance in the circulation systems in the body. Finally, if the condition for the relocalizing of them in other sites becomes appropriate, they produce new tumors in various parts of the body. The number of these circulating tumor cells (CTCs) in the blood is very rare. So, detecting and counting them is difficult, but very vital. There are various techniques for the detection of CTCs, which along with them, nanomaterials are suitable tools for this purpose due to their small sizes and unique properties. Because of the high efficiency of these materials, it is possible to exceed the other mentioned methods. In this review, we aim to render a comprehensive study about recent advances in the capture and subsequent release of the CTCs using different types of nanomaterials.
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KEYWORD
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CTC, nanomaterials, capture, release, detection
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